DEPARTMENT NAME
Department of Molecular Cell Mechanisms

CONTACT DETAILS FOR HEAD OF DEPARTMENT
Professor Jolanta Niewiarowska
jolanta.niewiarowska@umed.lodz.pl
+48 42 272 57 22

Department of Molecular Cell Mechanisms
ul. Mazowiecka 6/8
92-215 Lodz, Poland

TEAM MEMBERS
Professor Jolanta Niewiarowska
Katarzyna Sobierajska, Ph.D.
Magdalena Wiktorska, Ph.D.
Izabela Sacewicz-Hofman, Ph.D.
Wojciech Ciszewski, Ph.D.
Katarzyna Wieczorek, M.Sc.
Marta Wawro, M.Sc.

SHORT DESCRIPTION OF RESEARCH ACTIVITY

• Investigation of the molecular mechanisms involved in colorectal cancer progression, including epithelial and endothelial to mesenchymal transitions (EMT and EndMT)
• Characterization of the novel pathways engaged in the cytoskeleton reorganization (involving such proteins as MRTF, beta-tubulins and filamin A), which lead to the increased cell migration and invasiveness
• Analysis of the mechanisms regulating endothelial cell senescence that underlie pathologies of the cardiovascular system

DEPARTMENTAL ACHIEVEMENTS: PROJECTS AND PAPERS

Papers:

1. Wawro M.E.*, Sobierajska K.* Ciszewski W.M., Wagner W., Frontczak M., Wieczorek K., Niewiarowska J. CellSignal. 2017;38:26-38, IF-3.94.
2. Ciszewski W.M.*, Sobierajska K.*, Wawro M.E., Klopocka W., Chefczyńska N., Muzyczuk A., Siekacz K., WujkowskaA., Niewiarowska J. BBA-MRC 2017 S0167-4889(17)30233-1, IF-4.52.
3. Wieczorek K., Wiktorska M., Sacewicz-Hofman I., Boncela J., Lewiński A., Kowalska M.A., Niewiarowska J. Exp CellRes. 2017;359(1):163-170, IF-3.55.
4. Sobierajska K., Wieczorek K., Ciszewski W.M., Sacewicz-Hofman I., Wawro M.E., Wiktorska M., Boncela J.,Papiewska-Pajak I., Kwasniak P., Wyroba E., Cierniewski C.S., Niewiarowska J. BBA-MRC 2016 1863(9):2221-33; IF-5.13.
5. Pantsulaia I., Ciszewski W.N., Niewiarowska J. Ageing Res Rev. 2016;29:13-25; IF-7.53.

Projects:

1. MINIATURA; NCN; 2017-2018
2. MAESTRO; NCN; 2012-2018
3. MOMENTO; Polish-Norwegian Research Programme; NCRD; 2013-2016 4. HARC; EU; 2013-2016